The Daily PANCE and PANRE Extended Edition: Question 14

A polarized light microscopic study of joint fluid demonstrates negative birefringent crystals. What is the diagnosis?

  1. rheumatoid arthritis
  2. septic arthritis
  3. pseudogout gout
  4. aseptic arthritis
  5. gout

Answer: E


Uric acid (gout) is “Needle-shaped crystals with Negative birefringence) Calcium Pyrophosphate (pseudogout) is Prism-shaped crystals with Positive birefringence.

Know Your Content Blueprint

Gout/pseudogout are covered as part of the PANCE Musculoskeletal Blueprint

Review Topic: Gout/pseudogout

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