The Daily PANCE and PANRE Extended Edition: Question 32

A patient complains of marked weakness, nausea, vomiting and weight loss. His skin appears well-tanned, although he denies any sun exposure. The laboratory studies demonstrate an elevated potassium, a low sodium, and eosinophilia. What is the most likely diagnosis? 

  1. Cushing's syndrome
  2. Cushing's disease
  3. Addison's disease
  4. acromegaly
  5. scarlet fever

Anwer: C

Addison's disease

This is Addison's disease, autoimmune destruction of the entire adrenal gland. No Cortisol, increased ACTH (pigmentation), high K & low Na (no aldosterone).