Which of the following is most likely the cause of galactorrhea and amenorrhea?
- Sheehan's syndrome
- prolactin-secreting adenoma
- Frohlich's syndrome
- Cushing's disease
- a basophilic adenoma of the pituitary
Answer: B
Prolactin-secreting adenoma
Prolactin-secreting adenoma is the most common cause of galactorrhea/amenorrhea (after exclusion of pregnancy). I would choose Sheehan's syndrome if the question stated that the patient had a postpartum hemorrhage. The others do not cause this.
Know Your Content Blueprint
Pituitary adenoma and neoplasm is covered as part of the PANCE Endocrinology Blueprint
Review Topic: Pituitary adenoma and neoplasm