Chlamydia: The Daily PANCE Blueprint

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Chlamydia: The Daily PANCE Blueprint

A 28-year-old G1P0 female at 18 weeks gestation presents with mucopurulent discharge and dysuria. She is sexually active. Her vitals are unremarkable. UA is negative. Her Chlamydia trachomatis nucleic acid amplification test is positive. Which of the following is the best treatment option?

A. Doxycycline
B. Ceftriaxone
C. Ampicillin
D. Bactrim
E. Azithromycin

Answer and topic summary

The answer is E. Azithromycin

Chlamydia trachomatis is a gram-negative, obligate intracellular bacteria. It can be transmitted by sexual intercourse or vaginal birth (in an infected mother). It is one of the most common STIs and can lead to epididymitis, prostatitis, cervicitis, urethritis, etc. Most people are asymptomatic, but clinical features may include: purulent discharge, post-coital bleeding, dyspareunia, and dysuria. NAAT is the gold standard diagnostic tool. Treatment is doxycycline or azithromycin. Pregnant patients should be given azithromycin due to the teratogenic effects of doxycycline.

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Smarty PANCE Content Blueprint Review:

Covered under ⇒ PANCE Blueprint Infectious Disease ⇒ Bacterial Disease ⇒ Chlamydia

Also covered as part of the Family Medicine Rotation and Internal Medicine Rotation topic lists

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