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Metformin (Glumetza, Glucophage, Fortamet): Mechanism: Decreases hepatic glucose production and peripheral glucose utilization, decreases intestinal glucose absorption (these are reasons it leads to weight loss) Side effects: Can cause lactic acidosis and needs to be discontinued 24 hours before contrast and resumed 48 hours after with monitoring for creatinine, stop if creatine is > 1.5 Sulfonylureas -

19 Jun

Diabetes Medication: Mechanisms and Side Effects

Stephen Pasquini PA-C

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Contraindications, Diabetes, Function, Mechanism, medications, Side Effects

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Metformin (Glumetza, Glucophage, Fortamet): Mechanism: Decreases hepatic glucose production and peripheral glucose utilization, decreases intestinal glucose absorption (these are reasons it leads to weight loss) Side effects: Can cause lactic acidosis and needs to be discontinued 24 hours before contrast and resumed 48 hours after with monitoring for creatinine, stop if creatine is > 1.5 Sulfonylureas -

The NCCPA has updated the PANCE Content Blueprint for 2019! With the update came some changes here on my SMARTYPANCE Board Review Website and your board review checklist which I will be discussing in detail here. NCCPA PANCE Content Blueprint 2019 vs. 2018 The Big Changes The biggest change comes in the form of a

24 Apr

The Ultimate Guide to The New 2019 NCCPA PANCE Content Blueprint

Stephen Pasquini PA-C

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Boards, Content Blueprint, NCCPA, NEW, PA, PA Boards, PANCE, Physician Assistant, Review, Updates

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Content Blueprint

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The NCCPA has updated the PANCE Content Blueprint for 2019! With the update came some changes here on my SMARTYPANCE Board Review Website and your board review checklist which I will be discussing in detail here. NCCPA PANCE Content Blueprint 2019 vs. 2018 The Big Changes The biggest change comes in the form of a

Topic summaries with crucial PEARLS of wisdom covering all 13 NCCPA Content Blueprint Organs Systems (93 Blueprint Pearls in total) listed in alphabetical order and by Blueprint Organ System.

26 Feb

PANCE/PANRE Content Blueprint PEARLS

Stephen Pasquini PA-C

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Boards, Exam, NCCPA Content Blueprint, PA, PA Boards, PANCE, PANRE, Pearls, Physician Assistant, Summaries

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Topic summaries with crucial PEARLS of wisdom covering all 13 NCCPA Content Blueprint Organs Systems (93 Blueprint Pearls in total) listed in alphabetical order and by Blueprint Organ System.

Important Side Effects of Anti-Tubercular Drugs: Isoniazid (INH): Hepatotoxicity, B6 deficiencies, peripheral neuritis, cutaneous hypersensitivity, rarely can cause optic neuritis. Isoniazid is also associated with drug-induced lupus erythematosus. Rifampin (RMP): Hepatotoxicity, nephrotoxicity, red discoloration of the body fluids (which may be alarming but is completely benign), 'flu-syndrome,' and thrombocytopenic purpura. Rifampin is a well known P450 inducer and

03 Dec

The Important Side Effects of Anti-Tubercular Drugs

Stephen Pasquini PA-C

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BG, Ethambutol, Hepatotoxicity, INH, Isoniazid, Optic Neuritis, Pyrazinamide (PZA), Red, Rifampin, RMP

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Infectious Disease

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Important Side Effects of Anti-Tubercular Drugs: Isoniazid (INH): Hepatotoxicity, B6 deficiencies, peripheral neuritis, cutaneous hypersensitivity, rarely can cause optic neuritis. Isoniazid is also associated with drug-induced lupus erythematosus. Rifampin (RMP): Hepatotoxicity, nephrotoxicity, red discoloration of the body fluids (which may be alarming but is completely benign), 'flu-syndrome,' and thrombocytopenic purpura. Rifampin is a well known P450 inducer and

There are eight types of herpes viruses known to affect humans They are called the Herpes Human Viruses (HHV). There are two types of Herpes Simplex viruses: HSV 1- Oral lesions, HSV 2 - Genital lesions HSV 1 - Oral lesions (tongue, lips etc.) HSV 2 - Genital lesions (vulva, vagina, cervix, glans, prepuce, and penile shaft) HHV 3 - VZV (Varicella Zoster

01 Oct

Human Herpes (HHV) and Herpes Simplex (HSV) Viral Infections

Stephen Pasquini PA-C

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HHV, HSV1, HSV2, Human Herpes Virus

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There are eight types of herpes viruses known to affect humans They are called the Herpes Human Viruses (HHV). There are two types of Herpes Simplex viruses: HSV 1- Oral lesions, HSV 2 - Genital lesions HSV 1 - Oral lesions (tongue, lips etc.) HSV 2 - Genital lesions (vulva, vagina, cervix, glans, prepuce, and penile shaft) HHV 3 - VZV (Varicella Zoster

Typically impinges nerve below disc (ie: L4-L5 herniation causes L5 radiculopathy) Cervical radiculopathy: Spurling’s test: This test is typically done by having the patient bend the head to the side where symptoms have occurred (closing down the intervertebral foramen), and then gently apply pressure to the top of the head. C5 - bicep reflex C5 radiculopathy can

09 Aug

Radiculopathy Rapid Review: Cervical and Lumbar Patterns

Stephen Pasquini PA-C

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Cervical, Lumbar, Neurology, Radiculopathy

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Musculoskeletal, Neurology

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Typically impinges nerve below disc (ie: L4-L5 herniation causes L5 radiculopathy) Cervical radiculopathy: Spurling’s test: This test is typically done by having the patient bend the head to the side where symptoms have occurred (closing down the intervertebral foramen), and then gently apply pressure to the top of the head. C5 - bicep reflex C5 radiculopathy can

A Comparison of Hematologic Malignancies Below is a comparison table looking at the key features differentiating the six PANCE and PANRE hematological malignancies Quiz Yourself

05 Jul

Leukemia and Lymphoma: Comparison Table of Hematologic Malignancies

Stephen Pasquini PA-C

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ALL, AML, Boards, CLL, CML, Hematology, Hodgkins, Leukemia, Lymphoma, Non Hodgkin's Lymphoma, PANCE, PANRE, Review

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A Comparison of Hematologic Malignancies Below is a comparison table looking at the key features differentiating the six PANCE and PANRE hematological malignancies Quiz Yourself

The NCCPA™ Musculoskeletal Content Blueprint covers 3 general disorders of the knee Fractures and dislocations of the knee Osgood-Schlatter disease Soft tissue injuries of the knee Below are the most commonly referenced special examinations of the knee that you should know for your examination. *click the links below to view a video demonstration of the orthopedic exam in a pop-up

07 Feb

Special Examinations of the Knee

Stephen Pasquini PA-C

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EOR, Knee, Medical, Musculoskeltal, Orthopedics, PANCE, PANRE, Review

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Musculoskeletal

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The NCCPA™ Musculoskeletal Content Blueprint covers 3 general disorders of the knee Fractures and dislocations of the knee Osgood-Schlatter disease Soft tissue injuries of the knee Below are the most commonly referenced special examinations of the knee that you should know for your examination. *click the links below to view a video demonstration of the orthopedic exam in a pop-up

The NCCPA™ PANCE and PANRE GI and Nutrition Content Blueprint 6 types of Diseases of the Esophagus 5 types of Disorders of the Stomach 3 types of Diseases of the Gallbladder 3 types of Disorders of the Liver 2 types of Disorders of the Pancreas 13 types of Diseases of the Small Intestine and Colon

24 Oct

PANCE Gastroenterology and Nutrition PEARLS | NCCPA Content Blueprint

Stephen Pasquini PA-C

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Blueprint, Cheat Sheets, Gastroenterology, GI, Nutrition

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Gastroenterology and Nutrition

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The NCCPA™ PANCE and PANRE GI and Nutrition Content Blueprint 6 types of Diseases of the Esophagus 5 types of Disorders of the Stomach 3 types of Diseases of the Gallbladder 3 types of Disorders of the Liver 2 types of Disorders of the Pancreas 13 types of Diseases of the Small Intestine and Colon

The NCCPA™ PANCE and PANRE Genitourinary Content Blueprint 9 types of GU tract conditions 6 types of infectious and inflammatory conditions 5 types of GU neoplastic diseases 7 types of renal diseases 2 types of fluid and electrolyte disorders Acid Base Disorders Total: 30 conditions GU Tract Conditions (PEARLS) The NCCPA™ PANCE and PANRE Genitourinary Content

22 Oct

PANCE Genitourinary Pearls | NCCPA Content Blueprint

Stephen Pasquini PA-C

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Genitourinary, GU, PANCE, PANRE, Pearls, Summary, Tables

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The NCCPA™ PANCE and PANRE Genitourinary Content Blueprint 9 types of GU tract conditions 6 types of infectious and inflammatory conditions 5 types of GU neoplastic diseases 7 types of renal diseases 2 types of fluid and electrolyte disorders Acid Base Disorders Total: 30 conditions GU Tract Conditions (PEARLS) The NCCPA™ PANCE and PANRE Genitourinary Content

Dermatology PANCE and PANRE Blueprint PEARLS This is a comprehensive list following the exact NCCPA PANCE and PANRE Dermatology content blueprint The dermatology section represents 5% of your PANCE and PANRE board exam Make sure to download my FREE content blueprint checklist Members have access to the comprehensive 66 question dermatology exam Dermatology Pearls Flashcards Dermatology Pearls

09 Sep

Dermatology PANCE and PANRE Blueprint PEARLS

Stephen Pasquini PA-C

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dermatology, Pearls

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Dermatology, PEARLS

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Dermatology PANCE and PANRE Blueprint PEARLS This is a comprehensive list following the exact NCCPA PANCE and PANRE Dermatology content blueprint The dermatology section represents 5% of your PANCE and PANRE board exam Make sure to download my FREE content blueprint checklist Members have access to the comprehensive 66 question dermatology exam Dermatology Pearls Flashcards Dermatology Pearls

GI and Nutrition Content Blueprint Classic and Pathognomonic Patient Presentations and Question Stems For the PANCE and PANRE Board Exam GI Content Blueprint Case Presentation Flashcards Esophagus Esophagitis Patient will present with → odynophagia (painful swallowing), dysphagia and retrosternal chest pain Motility disorders Achalasia - Patient will present with → dysphagia to both liquids and solids,

12 Jun

GI and Nutrtition PANCE and PANRE Blueprint Classic Patient Presentations

Stephen Pasquini PA-C

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Clinical Presentations, Common, Content Blueprint, Gastroenterology, GI, Nutrition, PANCE, PANRE, Question Stems

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Gastroenterology and Nutrition, Question Stems and Patient Presentations

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GI and Nutrition Content Blueprint Classic and Pathognomonic Patient Presentations and Question Stems For the PANCE and PANRE Board Exam GI Content Blueprint Case Presentation Flashcards Esophagus Esophagitis Patient will present with → odynophagia (painful swallowing), dysphagia and retrosternal chest pain Motility disorders Achalasia - Patient will present with → dysphagia to both liquids and solids,

Endocrinology Content Blueprint Classic and Pathognomonic Patient Presentations and Question Stems

30 May

Endocrinology PANCE and PANRE Blueprint Classic Patient Presentations

Stephen Pasquini PA-C

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Clinical Presentations, Endocrinology, Pearls, Question Stems

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Endocrinology, Question Stems and Patient Presentations

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Endocrinology Content Blueprint Classic and Pathognomonic Patient Presentations and Question Stems

Pulmonary Content Blueprint Classic and Pathognomonic Patient Presentations and Question Stems Quiz Yourself

02 May

Pulmonology Blueprint PANCE and PANRE Classic Patient Presentations

Stephen Pasquini PA-C

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Common, Patient Presentations, Pulmonology, Question Stems

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Pulmonary, Question Stems and Patient Presentations

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Pulmonary Content Blueprint Classic and Pathognomonic Patient Presentations and Question Stems Quiz Yourself

EENT PANCE and PANRE NCCPA Content Blueprint (9%) EENT Common Patient Presentations Below is a list of the most common PANCE and PANRE board review question stems and patient presentations from the SMARTYPANCE EENT Content Blueprint board review. These case presentations represent the most common pathognomonic findings associated with each content blueprint EENT board review topic. You can

01 May

EENT PANCE and PANRE Content Blueprint Patient Presentations

Stephen Pasquini PA-C

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Clinical Presentations, Common, Content Blueprint, HEENT, Patient Presentations, Pearls, Question Stems

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EENT, Question Stems and Patient Presentations

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EENT PANCE and PANRE NCCPA Content Blueprint (9%) EENT Common Patient Presentations Below is a list of the most common PANCE and PANRE board review question stems and patient presentations from the SMARTYPANCE EENT Content Blueprint board review. These case presentations represent the most common pathognomonic findings associated with each content blueprint EENT board review topic. You can

Condition Incubation period Prodrome Rash Other Dx features Measles (Rubeola) 9-14 days Fever Cough, Conjunctivitis Rhinitis Maculopapular – face to extremities Koplik spots in mouth Mumps (Parotitis) 12-25 days Pain/swelling in front of/below ear Rubella (German Measles) 14-21 None Maculopapular – rapid spread from head to toe Teratogenic,

12 Mar

Comparison Table of Viral Exanthems

Stephen Pasquini PA-C

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dermatology, Exanthems, Rash, Viral

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Condition Incubation period Prodrome Rash Other Dx features Measles (Rubeola) 9-14 days Fever Cough, Conjunctivitis Rhinitis Maculopapular – face to extremities Koplik spots in mouth Mumps (Parotitis) 12-25 days Pain/swelling in front of/below ear Rubella (German Measles) 14-21 None Maculopapular – rapid spread from head to toe Teratogenic,

30 Jan

Matching Erythema

Stephen Pasquini PA-C

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03 Jan

9 Rashes That Affect the Palms and Soles

Stephen Pasquini PA-C

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dermatology, Rashes

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Hypertensive therapies recommended for treating coexisting conditions: Angina β-blockers, CCB Post Myocardial Infarction β-blockers, ACE Inhibitors Systolic Heart Failure ACEI/ARB, β-blockers, diuretics Diabetes mellitus/Chronic kidney disease ACEI/ARB Isolated systolic HTN in elderly Diuretics, CCB osteoporosis Thiazides BPH α1 blockers African Americans Thiazides, CCB Young white males Thiazides → ACEI/ARB → β-blockers Gout CCB, Losartan is the only ARB

10 Dec

Blood Pressure Medications for Specific Conditions

Stephen Pasquini PA-C

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Blood pressure, Cardiology, Hypertension, pharmacology

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Cardiovascular, Pharmacology

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Hypertensive therapies recommended for treating coexisting conditions: Angina β-blockers, CCB Post Myocardial Infarction β-blockers, ACE Inhibitors Systolic Heart Failure ACEI/ARB, β-blockers, diuretics Diabetes mellitus/Chronic kidney disease ACEI/ARB Isolated systolic HTN in elderly Diuretics, CCB osteoporosis Thiazides BPH α1 blockers African Americans Thiazides, CCB Young white males Thiazides → ACEI/ARB → β-blockers Gout CCB, Losartan is the only ARB

The most common BP meds and facts you need to know for your board exam Ace inhibitors are associated with cough, angioedema and can cause hyperkalemia. They are contraindicated in pregnancy. Spironolactone (a potassium sparing diuretic) can also cause hyperkalemia β blockers are contraindicated in Asthma and may cause impotence CCB cause leg edema, verapamil and diltiazem are rate

08 Dec

Six Blood Pressure Medication facts to know for your PANRE

Stephen Pasquini PA-C

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Cardiovascular, PANCE and PANRE Quick Tips

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The most common BP meds and facts you need to know for your board exam Ace inhibitors are associated with cough, angioedema and can cause hyperkalemia. They are contraindicated in pregnancy. Spironolactone (a potassium sparing diuretic) can also cause hyperkalemia β blockers are contraindicated in Asthma and may cause impotence CCB cause leg edema, verapamil and diltiazem are rate

From the PANCE and PANRE Gastroenterology content blueprint board review

05 Dec

Infectious Diarrhea Cheat Sheet and Quiz

Stephen Pasquini PA-C

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Cheat Sheets, Gastroenterology

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Gastroenterology and Nutrition

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From the PANCE and PANRE Gastroenterology content blueprint board review

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