Perioral dermatitis: The Daily PANCE Blueprint
Which of the following is the most consistent trigger of perioral dermatitis?
A. Androgen excess
B. Cutibacterium acnes overgrowth
C. Chronic topical corticosteroid use
D. Malassezia furfur infection
E. Contact allergy to cosmetics
Answer and topic summary
The answer is C. Chronic topical corticosteroid use
Perioral dermatitis presents as erythematous papules and pustules around the mouth, especially in the nasolabial folds and chin, with a characteristic 1–2 mm clear “Grenz zone” sparing the vermilion border. It most commonly affects young to middle-aged women but can occur at any age. The exact cause is unclear, though topical facial corticosteroid use is the most consistent trigger. Treatment includes discontinuation of topical steroids (with gradual tapering using low-potency agents if needed to reduce rebound). Oral tetracyclines have the strongest evidence for patients over age 8. Topical metronidazole (applied once or twice daily) is an effective alternative, particularly in children.
View blueprint lesson
Smarty PANCE Content Blueprint Review:
Covered under ⇒ PANCE Blueprint Dermatology ⇒ ⇒
