Papulosquamous Disorders: The Daily PANCE Blueprint

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Papulosquamous Disorders: The Daily PANCE Blueprint

A 42-year-old female presents to the clinic with a new weird “skin spot.” On physical exam, you notice sharply demarcated erythematous plaques with a dusky hue on the face and hands. She says she recently started Bactrim for a urinary tract infection. Which of the following is the most liked diagnosis?

A. Fixed drug eruption
B. Tinea corporis
C. Erythema annulare centrifugum
D. Erythema nodosum
E. Urticaria dermatitis

Answer and topic summary

The answer is A. Fixed drug eruption

A drug eruption is an adverse dermatologic reaction to a drug. Many different drugs can cause it, including but not limited to: antibiotics, NSAIDs, chemotherapy agents, AEDs, and antipsychotics. The lesions/rash can look quite different. Drug eruptions can be morbilliform, pustular, lichenoid, exfoliate, urticaria, bullous, photoallergic, etc. Diagnosis is clinical. Treatment is avoiding the causative medication. Remember there can be severe cases: such as Sevens-Johnson syndrome, DRESS (drug-reaction with eosinophilia and systemic symptoms).

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Smarty PANCE Content Blueprint Review:

Covered under ⇒ PANCE Blueprint Dermatology ⇒ Papulosquamous Disorders ⇒ Drug eruptions

Also covered as part of the Emergency Medicine EOR, Family Medicine EOR, Pediatric EOR, and General Surgery EOR topic lists

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