Erythema Infectiosum: The Daily PANCE Blueprint

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Erythema Infectiosum: The Daily PANCE Blueprint

A 5-year-old male presents to the clinic with a rash and fever. According to his mother, he initially developed a bilateral rash on his face, which then progressed to a reddish rash on both his lower and upper extremities. On exam, the rash appears to be maculopapular with a lacy-like appearance. What is the most likely diagnosis?

A. Kawasaki
B. Hand-foot-and-mouth disease
C. Rubella
D. Roseola
E. Erythema infectiosum

Answer and topic summary

The answer is E. Erythema infectiosum

Erythema infectiosum, also known as 5th disease, is a viral infection caused by the parvovirus B19. Usually it occurs in children between 5 and 15 years old. Transmission is mainly via droplets from respiratory secretions. Classic clinical findings include fever, a malar rash involving the cheeks with oral pallor (“slapped cheek rash”) that progresses into a maculopapular rash on the extremities (with a reticular or lacy-like appearance; usually on extensor surfaces). The disease usually resolves on its own. Symptom management should be given as indicated (e.g., Tylenol for fevers).

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Smarty PANCE Content Blueprint Review:

Covered under ⇒ PANCE Blueprint Infectious Disease ⇒ Viral Infectious Disease ⇒ Erythema infectiosum

Also covered as part of the Pediatric Rotation EOR topic list

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