Gastroparesis: The Daily PANCE Blueprint

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Gastroparesis: The Daily PANCE Blueprint

A 53-year-old female presents to the clinic complaining of early satiety, nausea, and a bloated feeling that worsens after meals. These symptoms have been progressively worsening over the past six months. She has a past medical history of type 2 diabetes mellitus managed with oral hypoglycemics. Physical examination reveals a soft, non-distended abdomen with normal bowel sounds. Given her diabetes history and symptoms, a gastric emptying study is performed and confirms delayed gastric emptying. Which of the following is the most appropriate initial treatment for this condition?

A. Nortriptyline
B. Loperamide
C. Metoclopramide
D. Omeprazole
E. Propranolol

Answer and topic summary

The answer is C. Metoclopramide

Metoclopramide is a prokinetic agent that enhances gastric motility and accelerates gastric emptying, which is beneficial in the management of gastroparesis. It works by increasing the amplitude of gastric contractions and the relaxation of the pyloric sphincter, facilitating gastric emptying without affecting gastric secretions.

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Smarty PANCE Content Blueprint Review:

Covered under ⇒ PANCE Blueprint GI and Nutrition ⇒ Gastric Disorders ⇒ Gastroparesis