Genital HSV infection and pregnancy: The Daily PANCE Blueprint

Genital HSV infection and pregnancy: The Daily PANCE Blueprint

A 23-year-old pregnant woman at 18 weeks gestation presents with vaginal lesions. PCR is positive for HSV-2. She has no prior history of genital herpes. Which of the following is recommended regarding delivery management?

A. Cesarean delivery at 39 weeks
B. Induction of labor at 37 weeks
C. Cesarean delivery only if active lesions are present at time of delivery
D. Artificial rupture of membranes after 39 weeks
E. Scheduled cesarean delivery at 34 weeks

Answer and topic summary

The answer is C) Cesarean delivery only if active lesions are present at time of delivery

This patient acquired a primary HSV-2 infection in the second trimester. She is at risk for viral shedding at delivery. However, the risk is substantially lower compared to acquiring infection late in the third trimester. Guidelines recommend cesarean delivery for active lesions at the time of delivery but not scheduled cesarean based on the timing of her infection. Therefore, cesarean is indicated only if she has active lesions or prodromal symptoms at the time of delivery.

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Smarty PANCE Content Blueprint Review:

Covered under ⇒ PANCE Blueprint Infectious DiseasePrenatal transmission of disorders ⇒ Genital herpes simplex virus infection and pregnancy

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