Gonococcal infections: The Daily PANCE Blueprint
A 22-year-old man presents to the clinic with a 3-day history of painful urination and purulent urethral discharge. He reports having unprotected sexual intercourse with a new partner 5 days ago. Gram stain of the urethral discharge shows numerous polymorphonuclear leukocytes and intracellular gram-negative diplococci. Culture confirms Neisseria gonorrhoeae infection. The patient is allergic to penicillin and reports a previous severe reaction to cephalosporins. Which of the following is the most appropriate treatment for this patient?
A. Azithromycin 2 g orally as a single dose
B. Doxycycline 100 mg orally twice daily for 7 days
C. Gentamicin 240 mg intramuscularly plus azithromycin 2 g orally, both as single doses
D. Ciprofloxacin 500 mg orally as a single dose
E. Cefixime 800 mg orally as a single dose
Smarty PANCE Content Blueprint Review:
Covered under ⇒ PANCE Blueprint Infectious Disease ⇒ Bacterial Disease ⇒ Gonococcal infections