Gynecomastia: The Daily PANCE Blueprint
Which of the following medications is NOT known to cause gynecomastia as a side effect?
A. Ketoconazole
B. Cimetidine
C. Finasteride
D. Spironolactone
E. Atenolol
Answer and topic summary
The answer is E. Atenolol
Gynecomastia is defined as mammary gland tissue proliferation in males. It can be due to an increased estrogen/testosterone ratio but can also be idiopathic as well. Specific causes include cancer, hyperthyroidism, Klinefelter syndrome, CKD, hypogonadism, and medications (e.g., finasteride, cimetidine, ketoconazole, spironolactone, androgenic steroids, opioids, etc). Workup may include CMP, thyroid function test, sex hormone profile, AFP, hCG, etc. Imaging is not routinely recommended. Treatment includes managing the underlying cause.
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