Horseshoe Kidney: The Daily PANCE Blueprint
Which of the following chromosomal abnormalities is associated with an increased risk of having a horseshoe kidney?
A. XO
B. Trisomy 18
C. Trisomy 21
D. XXY
E. None of the above
Answer and topic summary
The answer is A. XO
Horseshoe kidneys are the most common fusion defect of the kidneys. No clear genetic cause has been described even though horseshoe kidneys are more common in people with Turner Syndrome (XO) and sometimes it runs in families. Most horseshoe kidneys result from the fusion of the lower poles and are located around the origin of the inferior mesenteric artery. They are often asymptomatic and discovered incidentally on imaging. If patients do have symptoms, often they will have abdominal pain, frequent kidney stones, or UTIs. Diagnosis is made with US, CT, or MRI. No treatment is usually needed. Unfortunately, this does increase their risk for renal cancer.
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Smarty PANCE Content Blueprint Review:
Covered under ⇒ PANCE Blueprint Renal System ⇒ ⇒
