Movement Disorders: The Daily PANCE Blueprint
A 52-year-old woman presents to the neurology clinic with progressive difficulties in motor coordination and cognitive function over the past 18 months. She reports involuntary movements, especially in her limbs, memory lapses, and significant changes in mood, including increased irritability and impulsivity. Her family history is notable for a father who died in his 50s from a similar neurodegenerative condition. The patient’s social history is unremarkable. Neurological examination reveals choreiform movements, impaired balance, and decreased cognitive abilities. Which of the following tests is the most appropriate to confirm the suspected diagnosis?
A. Brain MRI
B. Serum ceruloplasmin level
C. Genetic testing
D. Lumbar puncture
E. EEG (electroencephalogram)
Smarty PANCE Content Blueprint Review:
Covered under ⇒ PANCE Blueprint Neurology ⇒ Movement Disorders ⇒ Huntington Disease
Also covered as part of the Internal Medicine EOR topic list