Osteosarcoma: The Daily PANCE Blueprint
Which of the following cancers is most commonly associated with a “sunburst appearance” of the bone on radiographic imaging?
A. Chordoma
B. Malignant fibrous histiocytoma
C. Chondrosarcoma
D. Ewing sarcoma
E. Osteosarcoma
Answer and topic summary
The answer is E. Osteosarcoma
Osteosarcoma is a type of malignant bone tumor that arises from osteoblasts (mesenchymal stem cells) in the periosteum. It is one of the most common primary bone cancers. Clinical features include pain (which worsens at night), swelling, limping, decreased ROM, and fractures. The tumor is usually found in the metaphases of long bones, such as the femur or tibia. An X-ray may show the classic sunburst appearance or Codman triangle. MRI should be obtained. A biopsy is needed for diagnosis. Treatment is surgery with adjuvant polychemotherapy.
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Smarty PANCE Content Blueprint Review:
Covered under ⇒ PANCE Blueprint Musculoskeletal ⇒ Neoplasms