Peyronie’s Disease: The Daily PANCE Blueprint
A 55-year-old male presents to your clinic complaining of curved, painful erections. You suspect Peyronie's disease. Which of the following other condition does this patient also most likely have?
A. Renal cell carcinoma
B. Hypothyroidism
C. Dupuytren's contracture
D. Carpal tunnel syndrome
E. Prostatitis
Answer and topic summary
The answer is C. Dupuytren’s contracture
Peyronie’s disease (PD) is a localized fibrotic disorder of the tunica albuginea that occurs in about 5% of males. Simply put, fibrosis scar tissue develops inside the penis and leads to curved, painful erections (+/- erectile dysfunction). The cause is multifactorial (genetics, trauma, tissue ischemia). Risk factors include genital/perineal injuries, urethral instrumentation, older age, underlying connective tissue disorder, Paget disease, gout, smoking, diabetes, etc. About 20% of patients with PD also have Duputreyn’s contraction. Diagnosis is usually apparent from patient history and examination. A urology referral is recommended if the condition is suspected. Management options include observation, medical therapy (e.g., pentoxifylline or intralesional collagenase Clostridium histolyticum injections), or surgery, depending upon the severity of the disease.
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Covered under ⇒ PANCE Blueprint Genitourinary ⇒ ⇒
Also found in Pediatrics EOR content blueprint
