Polyarteritis Nodosa: The Daily PANCE Blueprint

Polyarteritis Nodosa: The Daily PANCE Blueprint

Which of the following diagnostic studies will confirm a suspected diagnosis of polyarteritis nodosa?

A. Testing for rheumatoid factor (RF) and anti-cyclic citrullinated peptide (CCP) antibodies
B. Chest radiography
C. Measurement of muscle enzyme concentrations
D. Tissue biopsy
E. Serum complement levels

Answer and topic summary

The answer is D. Tissue biopsy

A tissue biopsy is the most definitive diagnostic study for confirming a diagnosis of polyarteritis nodosa. The biopsy, typically taken from an affected organ or tissue, can reveal the characteristic findings of necrotizing inflammation in medium-sized arteries. This finding is crucial for the diagnosis of polyarteritis nodosa and helps differentiate it from other vasculitides.

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Smarty PANCE Content Blueprint Review:

Covered under ⇒ PANCE Blueprint Musculoskeletal ⇒ Rheumatologic Disorders ⇒ Polymyalgia rheumatica

Also covered as part of the Internal Medicine PAEA EOR topic list