Trichomoniasis: The Daily PANCE Blueprint

Trichomoniasis: The Daily PANCE Blueprint

A 33-year-old female presents to your clinic with vulvar pruritus and vaginal discharge. On pelvic exam, you notice a frothy yellow-greenish discharge that is foul-smelling as well as small hemorrhages visible on the cervix. Which of the following is the preferred treatment for the most likely diagnosis?

A. Ceftriaxone
B. Acyclovir
C. Doxycycline
D. Amoxicillin
E. Metronidazole

Answer and topic summary

The answer is E. Metronidazole

Trichomoniasis is a genitourinary infection caused by the Trichomonas vaginalis, a flagellated protozoan. It is the most common non-viral STI worldwide and more commonly impacts females than males. Clinical features in females include a purulent, malodorous thin discharge, vaginal burning and pruritus, urinary frequency, and dyspareunia. On physical exam you may see erythema of the vulva and vaginal mucosa, as well as green-yellow discharge. Small hemorrhages may be visible on the cervix (i.e., “strawberry cervix”). The preferred diagnostic test is NAAT (sensitivity and specificity 100%). If the pH is obtained, it will usually be above 5.0. Treatment is metronidazole 2 grams PO for the patient and all sex partners. Patients should also be educated on the consistent use of condoms.

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