Asthma: The Daily PANCE Blueprint
A 16-year-old presents with intermittent wheezing and shortness of breath during soccer practice. Spirometry shows an obstructive pattern (FEV1/FVC < 0.70). After administration of albuterol, which finding would confirm a diagnosis of asthma?
A. FEV1/FVC ratio < 0.70
B. >12% increase in FEV1
C. >12% increase in FVC
D. <12% increase in FEV1
E. Increased Total Lung Capacity
Answer and topic summary
The answer is B. >12% increase in FEV1
The hallmark of asthma is reversible airway obstruction. Once obstruction is demonstrated (FEV1/FVC < 0.70), a bronchodilator is given to assess reversibility. An increase in FEV1 of >12% and at least 200 mL from baseline after albuterol confirms asthma. This reflects improved expiratory airflow due to relaxation of bronchial smooth muscle. Management typically involves inhaled corticosteroids for control and short-acting beta-agonists for rescue.
Incorrect answer explanations:
- FEV1/FVC ratio < 0.70 – Confirms obstruction but not reversibility; could be COPD.
- >12% increase in FVC – FVC is not the standard parameter for asthma reversibility.
- <12% increase in FEV1 – Suggests fixed obstruction, more consistent with COPD.
- Increased Total Lung Capacity – Indicates hyperinflation/air trapping, not diagnostic for asthma.
View blueprint lesson
Smarty PANCE Content Blueprint Review:
Covered under ⇒ PANCE Blueprint Pulmonary ⇒ ⇒
