Herpes Simplex: The Daily PANCE Blueprint
A 22-year-old female presents with pain and tingling around her mouth, followed by the appearance of vesicles that progressed to painful ulcers along the lip borders and oral mucosa. Which of the following is the most likely diagnosis?
A. Aphthous stomatitis
B. Oral candidiasis
C. Herpetic gingivostomatitis
D. Herpes Labialis
E. Impetigo
Answer and topic summary
The answer is D. Herpes Labialis
Herpes simplex virus infections are common and are caused by 2 main genotypes: HSV-1 and HSV-2. Infection location differs but can include herpetic whitlow, eczema herpeticum, herpetic gingivostomatitis, labial herpes (aka cold sores), and genital herpes. Transmission occurs due to direct contact with mucosal tissue or secretions. Labial herpes classically presents as pain/tingling around the mouth and then vesicles that become painful ulcerations on the lip borders and oral mucosa. The treatment is acyclovir.
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