Breast cancer: The Daily PANCE Blueprint
A 48-year-old female presents with a painless, firm breast mass in the upper outer quadrant. Which of the following is the most common histologic type of breast cancer?
A. Invasive lobular carcinoma
B. Ductal carcinoma in situ
C. Mucinous carcinoma
D. Medullary carcinoma
E. Invasive ductal carcinoma
Answer and topic summary
The answer is E. Invasive ductal carcinoma
Pemphigus vulgaris is a life-threatening dermatologic disorder characterized by blister formation in the skin and mucous membranes. It is classified as a Type II hypersensitivity reaction. Precipitating factors include dietary changes, UV radiation, viral infections, and certain medications (e.g., captopril or penicillamine). Clinical features may include painful, flaccid blisters (commonly with mucosal involvement), erosions, and crusts. The Nikolsky sign (mechanical pressure at the edge of blisters leads to induction of blistering and sloughing off of epidermis/skin) will be positive. Diagnosis is confirmed with a biopsy. Rituximab combined with systemic corticosteroids is now the most appropriate first-line treatment for moderate-to-severe pemphigus vulgaris.
View blueprint lesson
Smarty PANCE Content Blueprint Review:
Covered under ⇒ PANCE Blueprint Reproductive System ⇒ ⇒
Also covered as part of the Family Medicine EOR, and Women's Health EOR topic lists
