Feeding and eating disorders: The Daily PANCE Blueprint
Which medication is clearly contraindicated in patients with anorexia and bulimia?
A. Bupropion
B. Fluoxetine
C. Olanzapine
D. Topiramate
E. Sertraline
Answer and topic summary
The answer is A) Bupropion
Bupropion, an antidepressant, is contraindicated in patients with eating disorders like anorexia and bulimia due to an increased risk of seizures. These disorders often lead to electrolyte imbalances, particularly hypokalemia, and hypomagnesemia, which can lower the seizure threshold. Bupropion has a proconvulsant effect, especially at higher doses, which further increases this risk.
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