Impetigo: The Daily PANCE Blueprint

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Impetigo: The Daily PANCE Blueprint

What is the preferred antibiotic regimen for extensive impetigo (patients with numerous impetigo lesions or ecthyma) in children?

A. Topical mupirocin x 10 days
B. Topical retapamulin x 5 days
C. Cephalexin x 7 days
D. Amoxicillin x 10 days
E. TMP-SMX x 7 days

Answer and topic summary

The answer is C. Cephalexin x 7 days

Extensive impetigo or ecthyma (deep impetigo) is best treated with oral antibiotics, particularly in cases with numerous lesions. Cephalexin (500 mg QID) and dicloxacillin (500 mg QID) are first-line oral options for impetigo due to their effectiveness against Staphylococcus aureus and Streptococcus pyogenes. A 7-day course is typically sufficient. For methicillin-resistant Staphylococcus aureus (MRSA), trimethoprim-sulfamethoxazole, clindamycin, or doxycycline is preferred.

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Smarty PANCE Content Blueprint Review:

Covered under ⇒ PANCE Blueprint Dermatology ⇒ Dermatologic Infectious diseases (PEARLS) ⇒ Bacterial Infections ⇒ Impetigo

Also covered on the Family Medicine EOR, Emergency Medicine EOR, and Pediatric rotation content topic list

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