Irritable Bowel Syndrome: The Daily PANCE Blueprint

Irritable Bowel Syndrome: The Daily PANCE Blueprint

A 29-year-old woman presents with intermittent abdominal pain and altered bowel habits, including periods of diarrhea alternating with constipation, over the past 6 months. Her symptoms improve with defecation. There is no weight loss, GI bleeding, or nocturnal symptoms. Laboratory studies, including CBC, CRP, and stool studies, are unremarkable. What diagnostic criteria are most appropriate for confirming this patient’s condition?

A. Ranson criteria
B. Rome IV criteria
C. Manning criteria
D. Glasgow-Blatchford score
E. Light’s criteria

Answer and topic summary

The answer is B. Rome IV criteria

Irritable bowel syndrome is a chronic GI disorder characterized by abdominal pain, changes in bowel habits, and bloating with NO organic cause. It’s very common and accounts for up to 50% of visits to gastroenterologists. The etiology is unknown, but some believe there may be an environmental trigger. Diagnosis is made by the Rome IV criteria. Initial labs depend on if the patient presents with constipation or diabetes, but may include CBC, CMP, TSH, serologic testing for celiac disease, fecal lactoferrin . Make sure to watch out for alarm signs that point to another, more serious diagnosis (e.g., overt GI bleeding, weight loss, palpable mass).

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Covered under ⇒ PANCE Blueprint GI and Nutrition ⇒ Colorectal disorders ⇒ Irritable bowel syndrome

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