Peptic Ulcer Disease: The Daily PANCE Blueprint

Peptic Ulcer Disease: The Daily PANCE Blueprint

A 55yo presents with gnawing epigastric pain RELIEVED by eating. What's the most likely diagnosis?

A. Gastric ulcer
B. Duodenal ulcer
C. GERD
D. Acute pancreatitis
E. Gastritis

Answer and topic summary

The answer is B. Duodenal ulcer

Duodenal ulcer pain improves with meals because food buffers gastric acid. Pain often returns 2–3 hours after eating or at night. Most cases are due to H. pylori infection or NSAID use.

Board Pearl:

  • 👉 Pain better with food = duodenal ulcer
  • 👉 Pain worse with food = gastric ulcer
View blueprint lesson

Smarty PANCE Content Blueprint Review:

Covered under ⇒ PANCE Blueprint GI and Nutrition ⇒ Gastric Disorders ⇒ Peptic ulcer disease

Also covered as part of the Internal Medicine EOREmergency Medicine EORFamily Medicine EOR, and General Surgery EOR topic list

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