Stasis Dermatitis: The Daily PANCE Blueprint
Which of the following best explains the pathophysiology of stasis dermatitis?
A. Venous hypertension, localized inflammatory reaction, RBC extravasation
B. T-cell mediated autoimmune reaction against basal epithelial keratinocytes
C. Lack of blood flow in the venous system leads to apoptosis of columnar cells
D. Valvular dysfunction in veins causing venous hypotension
E. None of the above
Answer and topic summary
The answer is A. Venous hypertension, localized inflammatory reaction, RBC extravasation
Stasis dermatitis is a dermatologic manifestation of venous insufficiency. The localized inflammatory reaction leads to the proliferation of small blood vessels, perivascular lymphocytic infiltration, extravasated erythrocytes, and hemosiderin-laden macrophages. On physical exam, you will see an erythematous, scaling, eczematous patch on the lower legs. It is often associated with other signs of venous insufficiency, such as varicose veins, chronic dependent edema, and ulcerations. Common risk factors for venous insufficiency include prior DVT, smoking, advanced age, obesity, and prolonged standing. Initial treatment of peripheral venous insufficiency entails compression stockings, leg elevation, and exercise.
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Smarty PANCE Content Blueprint Review:
Covered under ⇒ PANCE Blueprint Dermatology ⇒ ⇒
This topic is not included as part of the EOR topic lists
