The Daily PANCE and PANRE Question 15

All of the following are factors that predispose a patient to the development of gastroesophageal reflux EXCEPT:

  1. hiatal hernia
  2. pregnancy
  3. scleroderma
  4. an incompetent esophageal sphincter
  5. pernicious anemia

Answer: E

Pernicious anemia

Pernicious anemia has no correlation with GERD. It is an autoimmune destruction of the gastric parietal cells that make intrinsic factor. Signs and symptoms are not present until B12 levels are very low (and include peripheral neuropathies & ataxia)

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