Vaginal and Vulvar Cancer: The Daily PANCE Blueprint
Which of the following strains of HPV are most likely indicated in vulvar cancer?
A. HPV 11
B. HPV 16
C. HPV 24
D. HPV 30
E. HPV 35
Answer and topic summary
The answer is B. HPV 16
Vulvar cancer is cancer of the outer female genitalia. Risk factors include smoking, HPV infection (especially 16, 18, 31, and 33), immunosuppression, and precancerous lesions. Clinical features may include burning, localized pruritus, new lumps/lesions (often wart-like), bleeding, and discharge. Diagnosis is made with a biopsy. The first line treatment is surgical resection (radical vulvectomy). It has a poor prognosis.
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