The Important Side Effects of Anti-Tubercular Drugs

The Important Side Effects of Anti-Tubercular Drugs

Important Side Effects Of Tuberculosis Medications

The Important Side Effects of Anti-Tubercular Drugs

Isoniazid (INH)

  • Hepatotoxicity
  • B6 deficiencies
  • Peripheral neuritis 
  • Cutaneous hypersensitivity
  • Rarely can cause optic neuritis 
  • Isoniazid is also associated with drug-induced lupus erythematosus

Rifampin (RMP)

  • Hepatotoxicity
  • Nephrotoxicity
  • Red discoloration of the body fluids (which may be alarming but is completely benign)
  • Flu-syndrome
  • Thrombocytopenic purpura
  • Rifampin is a well known P450 inducer and can increase the rate of metabolism of other drugs that are cleared by the liver through the p450 system

Pyrazinamide (PZA)

  • Hepatotoxicity
  • Hyperuricemia

Ethambutol (ETH)

  • This drug can be especially toxic to the eyes, with adverse effects of optic neuritis and red-green color blindness reported

Streptomycin (STM)

  • Nephrotoxicity, and ototoxicity

For more information visit the SMARTY PANCE Tuberculosis Lesson and view the interactive ReelDx video case.

The Daily PANCE and PANRE

Get 60 days of PANCE and PANRE Multiple Choice Board Review Questions delivered daily to your inbox. It's 100% FREE and 100% Awesome!

You have Successfully Subscribed!