Which white blood cell disorder is characterized by the presence of the Philadelphia chromosome in 90% of cases?
- chronic lymphocytic leukemia (CLL)
- acute lymphocytic leukemia (ALL)
- chronic myelogenous leukemia (CML)
- acute myelogenous leukemia (AML)
- multiple myeloma
Answer: C
Chronic Myeloid Leukemia (CML) - (Philadelphia CreaM cheese)
Philadelphia Chromosome occurs in CML. ALL occurs in children. AML is associated with Auer rods. Multiple myeloma has Bence-Jones protein. CLL has no clear distinguishing feature except increased lymphocytes.
Know Your Content Blueprint
Acute and chronic myeloid and lymphocytic leukemia is part of the NCCPA Content Blueprint Hematology System (3%)
Review Topic: chronic myeloid leukemia