Tuberculosis: The Daily PANCE Blueprint
Which of the following are the antibiotics of choice for an active tuberculosis infection?
A. rifampicin, ciprofloxacin, tobramycin, and amikacin
B. nitrofurantoin, amikacin, doxycycline, and ethambutol
C. doxycycline, tobramycin, nitrofurantoin, and ciprofloxacin
D. isoniazid, azithromycin, doxycycline, and pyrazinamide
E. ethambutol, rifampicin, pyrazinamide, isoniazid
Answer and topic summary
The answer is E. ethambutol, rifampicin, pyrazinamide, isoniazid
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Most people who are infected have latent TB; however, if the immune system is compromised, the infection can be reactivated and active TB can occur. Clinical features of active TB include night sweats, anorexia, fevers, chest pain, weight loss, productive cough, hemoptysis, etc. The gold standard for diagnosis is mycobacterial cultures. All patients with active TB should be screened for HIV. Treatment includes four antibiotics: rifampicin, isoniazid, ethambutol, and pyrazinamide aka RIPE (all four antibiotics for 2 months, followed by just the first two, respectively, for 4 more months). Patients’ liver enzymes should be monitored while on these medications because they all can be potentially hepatotoxic.
View blueprint lesson
Smarty PANCE Content Blueprint Review:
Covered under ⇒ PANCE Blueprint Pulmonary ⇒ ⇒
Also covered as part of the Family Medicine EOR, Emergency Medicine EOR, and Internal Medicine EOR topic lists
