PANCE Blueprint Renal System (5%)

• Glomerulonephritis
• Nephrotic syndrome
• Pyelonephritis

Acute kidney injury (acute renal failure)

Chronic kidney disease

Congenital or structural renal disorders

• Horseshoe kidney
• Hydronephrosis
• Polycystic kidney disease
• Renal vascular disease

End-stage renal disease

Fluid and electrolyte disorders

• Acid-base disorders
• Dehydration
• Hyperkalemia/hypokalemia
• Hypervolemia
• Hyponatremia

Neoplasms

• Renal cell carcinoma
• Wilms tumor

Here is a summary of the new additions/updates to the 2024 PANCE Renal System Blueprint that toook effect in 2025.

• The percentage remains the same (5%)
• Gone is the confusing category of “acute disorders,” which included the somewhat redundant subtopics of nephrotic syndrome and glomerulonephritis.
• Pyelonephritis has been moved to the GU System Blueprint under infectious disorders.
• Acute kidney injury and acute renal failure are now better categorized as intrinsic, prerenal, and postrenal. The topics of glomerulonephritis and nephrotic syndrome will be covered as part of this topic.
• The category of fluid and electrolyte disorders and its subtopics have been disassembled into two new topics: “electrolyte disorders” and “fluid imbalances.” Gone are the separate topics of dehydration, hyperkalemia/hypokalemia, hypervolemia, and hyponatremia.
• Renal vascular disease is now its own category.
• New category of rhabdomyolysis.