PANCE Blueprint Neurology (7%)

• Concussion
• Post-concussion syndrome
• Traumatic brain injury

Cranial nerve palsies

Encephalopathic disorders

Headaches

• Cluster headache
• Migraine
• Tension headache

Infectious disorders

• Encephalitis
• Meningitis

Movement disorders

• Essential tremor
• Huntington disease
• Parkinson disease
• Tourette disorder

Neoplasms (Benign and Malignant)

Neurocognitive disorders

• Delirium
• Major/mild neurocognitive disorders

Neuromuscular disorders 

• Cerebral palsy
• Multiple sclerosis
• Myasthenia gravis

Peripheral nerve disorders

• Carpal tunnel syndrome
• Complex regional pain syndrome
• Guillain-Barré syndrome
• Peripheral neuropathy

Seizure disorders

• Focal seizures
• Generalized seizures
• Status epilepticus

• Arteriovenous malformation
• Cerebral aneurysm
• Intracranial hemorrhage
• Stroke
• Syncope
• Transient ischemic attack

Neurologic System Exam

Here is a summary of the new additions/updates to the 2024 PANCE Neurologic System Blueprint that took effect in 2025.

• Vascular disorders have been renamed cerebrovascular disorders and moved to the beginning of the blueprint. Two new categories—coma and hydrocephalus (on the PANRE blueprint)—have been added.
• Movement disorders → added two new categories: restless legs syndrome and tardive dyskinesia.
• The category of “peripheral nerve disorders” has been changed to “nerve disorders,” along with the removal of carpal tunnel syndrome and the addition of the topic of mononeuropathies.
• Within the category of neurocognitive disorders → major/mild neurocognitive disorders have been replaced with “cognitive impairment.”

A new category of spinal cord syndromes has been created, covering three topics that are new to the neurologic system blueprint:

• Cauda equina syndrome (formerly part of the MSS system blueprint)
• Epidural abscess
• Spinal cord injuries