PANCE Blueprint Psychiatry (7%)

Trauma and stressor-related disorders (PEARLS)

DSM-5 Trauma and Stressor-Related Disorders

Items in bold are covered as part of the NCCPA PANCE/PANRE Psychiatry Blueprint and will be covered here. Additional topics may be covered in the PAEA EOR™ Psychiatry Topic List.

Trauma and stressor-related disorders
Adjustment disorders Prolonged negative emotional reaction following a major life stressor (e.g., divorce, moving, new job)
Post-traumatic stress disorder An anxiety disorder characterized by haunting memories, nightmares, social withdrawal, jumpy anxiety, and/or insomnia that lingers for four weeks or more after a traumatic experience
Acute stress disorder (ASD) Acute stress disorder is a period of intrusive recollections that occurs after witnessing or experiencing a traumatic event. ASD occurs within one month of the traumatic event and lasts from three days up to one month

Acute stress disorder (PANRE) (ASD)
Patient will present as →  a 25-year-old individual who was involved in a severe car accident three weeks ago. They report experiencing recurrentinvoluntary, and intrusive distressing memories of the car accident. They have been feeling on edge, have difficulty sleeping, and actively avoid reminders of the accident. They also feel detached from others and lose interest in activities they used to enjoy. The patient is diagnosed with acute stress disorder. Management includes trauma-focused cognitive behavioral therapy, with SSRIs considered if symptoms are severe. Close follow-up is recommended to assess for resolution or progression to PTSD.

Same symptoms as PTSD, but lasting 3 days to 1 month after the trauma

  • Dissociative symptoms (numbing, derealization, amnesia) are prominent in the acute window
  • Symptoms beyond 1 month → rediagnose as PTSD

DX: DSM-5 — trauma exposure + ≥ 9 of 14 symptoms across intrusion, negative mood, dissociation, avoidance, and arousal clusters, lasting 3 days to 1 month

  • Screen for concurrent injury, substances, and prior psychiatric history

TX: Trauma-focused CBT — reduces progression to PTSD

  • Benzodiazepines are not recommended and may worsen outcomes; no medication prevents PTSD

PTSD vs. ASD

Acute stress disorder is a period of intrusive recollections that occurs after witnessing or experiencing a traumatic event. The characteristics of this disorder differ from those of posttraumatic stress disorder in that ASD occurs within one month of the traumatic event and lasts from three days up to one month, whereas PTSD symptoms must last more than one month.

Adjustment disorders
Patient will present as → a 35-year-old female presents with sadness, irritability, and difficulty concentrating for two months following the unexpected loss of her job. She reports worry about her financial future and withdrawal from friends, but denies suicidal thoughts or prior mental health issues. Examination reveals a tearful individual with an anxious mood. Symptoms began within three months of the stressor and do not meet criteria for major depression. She is diagnosed with adjustment disorder with mixed anxiety and depressed mood. Management includes cognitive behavioral therapy (CBT) and supportive care, with a follow-up scheduled to monitor progress.

Disproportionate response to an identifiable stressor — beginning within 3 months, resolving within 6 months of the stressor's end

  • Common stressors: job loss, illness, marital/financial conflict, school problems, family illness or death
  • Specify: with depressed mood · with anxiety · mixed · with disturbance of conduct

DX: DSM-5 — emotional or behavioral symptoms within 3 months of a stressor, out of proportion to it or functionally impairing

  • Does not meet criteria for another mental disorder — if full major-depressive criteria are met, diagnose MDD instead
  • Resolves within 6 months after the stressor or its consequences end

TX: Psychotherapy is the treatment

  • Brief, targeted symptomatic medication (e.g., for sleep) only as needed; reassess for evolution into MDD
Bereavement and Grief Reaction
Patient will present as → a 42-year-old female presents with intense sadness, loss of appetite, and difficulty sleeping following the death of her husband three weeks ago. She reports crying frequently and feeling guilty, but denies thoughts of self-harm. Despite her grief, she continues to care for her children and perform daily tasks. Examination reveals a tearful but alert individual with appropriate affect. Screening for depression is negative. She is diagnosed with bereavement and provided psychological support. Referral to grief counseling is offered, and she is educated on signs of complicated grief. Follow-up is scheduled to monitor her progress.

Grief comes in WAVES triggered by reminders — with preserved self-esteem

  • Transient hallucinations of the deceased (hearing their voice) with intact insight can be normal
  • vs MDD: pervasive depressed mood, worthlessness, guilt unrelated to the deceased, suicidal ideation — an MDE can be diagnosed during bereavement when criteria are met
  • Prolonged grief disorder (DSM-5-TR): intense yearning/preoccupation nearly daily ≥ 12 months after the death (≥ 6 months in children) with impairment

DX: Clinical — distinguish normal grief from a major depressive episode and from prolonged grief disorder

  • Prolonged grief: ≥ 3 of 8 accompanying symptoms (identity disruption, disbelief, avoidance, numbness, meaninglessness…), exceeding cultural norms

TX: Support and time — no medication for normal grief

  • Grief-targeted psychotherapy for prolonged grief disorder — more effective than antidepressants; treat comorbid MDD when present
Post-traumatic stress disorder (PTSD)
Patient will present as → 33-year-old male presents with difficulty sleeping. The patient states that these symptoms began approximately 3 months ago when he lost his close friend while they were both in combat. He re-experiences this loss during the day and in his dreams. The patient reports anxiety and depression. 

Trauma + ≥ 1 month of intrusion, avoidance, negative mood/cognition, and hyperarousal

  • Symptoms < 1 month = acute stress disorder; specify with dissociative symptoms or delayed expression
  • Screen for comorbid depression, substance use, and suicidality (PC-PTSD-5 / PCL-5)

DX: DSM-5 — trauma exposure + symptoms from all 4 clusters: ≥ 1 intrusion · ≥ 1 avoidance · ≥ 2 negative cognition/mood · ≥ 2 arousal, lasting > 1 month with impairment

  • Exposure = direct, witnessed, learned-of (close family/friend), or repeated occupational exposure to aversive details

TX: Trauma-focused psychotherapy first-line (CPT, prolonged exposure, EMDR) and/or SSRIs/SNRIs (sertraline, paroxetine, venlafaxine)

  • Prazosin for trauma-related nightmares
  • Benzodiazepines are not recommended in PTSD
Non-substance-related addictive disorders (PANRE) (Lecture) (Prev Lesson)
(Next Lesson) Acute stress disorder (ASD) (PANRE) (Lecture)
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