Patient will present as → a 22-year-old female comes to the emergency department for a syncopal episode. Just prior to the syncopal episode, the patient experienced painful menstrual cramping. She experienced a cold sweat and palpitations with the cramping. The patient describes similar episodes to her menstrual cramps in the past. Her vital signs and physical examination are normal. ECG is unremarkable.
Vasovagal syncope (common faint) is characterized by an abrupt onset of hypotension followed by a syncopal episode often in reaction to a stressful trigger
- Caused by a paradoxical withdrawal of sympathetic stimulation and a replacement by enhanced parasympathetic (vagal) activity causing bradycardia, vasodilation, marked decrease in BP, and cerebral perfusion
- Most common cause of syncope. Most people have one episode, but for some, it is a recurrent problem
- Common triggers include strain, stress, long periods of standing, heat exposure, or the sight of blood
- Symptoms include paleness, nausea, sweating, a rapid heartbeat, and fainting
Comprehensive history, physical examination (which may include careful carotid sinus massage in older patients), and review of an electrocardiogram
- Upright tilt-table study can reproduce the symptoms in susceptible people
- Can occur at any age, but if the first episode is after age 40, be reluctant to make this diagnosis
Can usually be reversed by assuming the supine posture and elevating the legs
- Treatment usually involves trigger avoidance, but may on rare occasions include β-blockers and disopyramide or a pacemaker
Question 1 |
Arrhythmia Hint: Cardiovascular causes of syncope include arrhythmias, mechanical heart disease (e.g., aortic stenosis and hypertrophic cardiomyopathy), pulmonary embolism, aortic dissection, and cardiac tamponade. Patients with sudden onset syncope and trauma to the face (indicating an inability to brace the fall) should increase the reader’s suspicion for a cardiac etiology. | |
Orthostatic hypotension Hint: Orthostatic hypotension usually occurs in the presence of hypovolemia, dysautonomia, and/or certain medications (e.g., diuretics and β-blockers). Diagnosis can be made if systolic blood pressure decreases by ≥20 mm Hg or diastolic blood pressure decreases by ≥10 mm Hg when going from a sitting to a standing position, which was not seen in this patient. | |
Seizure Hint: Seizures technically do not meet the definition of syncope, since they are not caused by a disruption in cerebral blood flow. History that would indicate a seizure includes a preceding aura, tonic–clonic movements during the episode, and a postictal state (confusion with gradual improvement in neurologic function). | |
Vasovagal syncope | |
Aortic stenosis Hint: Cardiovascular causes of syncope include arrhythmias, mechanical heart disease (e.g., aortic stenosis and hypertrophic cardiomyopathy), pulmonary embolism, aortic dissection, and cardiac tamponade. Patients with sudden onset syncope and trauma to the face (indicating an inability to brace the fall) should increase the reader’s suspicion for a cardiac etiology. |