PANCE Blueprint Endocrinology (6%)

• Primary adrenal insufficiency
• Cushing syndrome

Diabetes mellitus

• Type 1
• Type 2

Hypogonadism

Neoplasms

• Multiple endocrine neoplasias
• Neoplastic syndrome
• Primary endocrine malignancy
• Syndrome of inappropriate antidiuretic hormone secretion (SIADH)

Parathyroid disorders

• Hyperparathyroidism
• Hypoparathyroidism

Pituitary disorders

• Acromegaly/gigantism
• Diabetes insipidus
• Dwarfism
• Pituitary adenoma

Thyroid disorders

• Hyperthyroidism
• Hypothyroidism
• Thyroiditis

Here is a summary of the new additions/updates to the 2024 PANCE Endocrine System Blueprint that took effect in January 2025.

• Adrenal disorders → New topic of pheochromocytoma (previously covered as part of adrenal neoplastic disease)
• Metabolic syndrome has its own category in the endocrinology blueprint → previously partnered with obesity in the GI Blueprint
• SIADH → has been relocated from neoplasms to the category of pituitary disorders
• Pituitary disorders → New topic of prolactinoma and Cushing disease
• Thyroid disorders → New topic of goiter and thyroid nodules