PANCE Blueprint Pulmonary (9%)

Croup (ReelDx)

REEL-DX-ENHANCED-PAID-MEMBERS-ONLY

croup (2)

2 y/o with cough and stridor

Patient will present as → a 2-year-old male is brought to the emergency department by his parents due to a 2-day history of low-grade fever, nasal congestion, and a barking cough" that worsened at night. Today, he developed stridor at rest and increasing respiratory distress. His temperature is 100.8°F (38.2°C), and he appears anxious with mild intercostal retractions. On auscultation, lung fields are clear but inspiratory stridor is audible. A soft tissue neck X-ray reveals subglottic narrowing ("steeple sign"). He is diagnosed with viral croup, likely due to parainfluenza virus. Management includes nebulized racemic epinephrine and dexamethasone, with observation for worsening symptoms. Parents are advised on supportive care, signs of respiratory distress, and when to return to the hospital.

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Croup is caused by parainfluenza virus

  • Commonly in children 6 months - 3 years of age
  • Fall and early winter months (same time of year as bronchiolitis)
  • Barking cough and stridor
What x-ray finding supports a diagnosis of croup?
“Steeple” sign on frontal CXR

Diagnosis is clinical, but AP neck X-ray may show the classic steeple sign (narrowing of the trachea in the subglottic region)

Croup steeple sign

AP x-ray of the neck in a child with croup demonstrating the steeple sign (narrowing of the trachea)

Mild cases are treated with humidified air or cool mist, and single-dose oral dexamethasone

  • Moderate to severe cases (stridor at rest or respiratory distress) require nebulized epinephrine and close monitoring
  • Hospitalization is considered for patients with worsening symptoms, poor oral intake, or hypoxia
  • Prognosis is excellent—complications include respiratory failure and secondary bacterial tracheitis, though rare

osmosis Osmosis
Picmonic
Picmonic Croup

IM_NUR_Croup_V1.1_

Croup is a general term that describes a group of conditions characterized by edema and inflammation of the upper airway. The focus of this Picmonic is on the most common croup disorder – laryngotracheobronchitis, often abbreviated as LTB, which often leads to hospitalization. The other group disorders are acute epiglottitis, acute spasmodic laryngitis, and acute tracheitis.

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Picmonic Parainfluenza Virus

parainfluenza-virus_5725_1482261879

Parainfluenza virus is a single-stranded RNA paramyxovirus that causes croup in children. Croup is an upper respiratory infection that presents with respiratory difficulty and a characteristic barking cough. In adults, it causes mild upper respiratory infections. However, parainfluenza infections can cause inflammation and swelling in the upper airway to the point of obstruction in children. Severe cases present with inspiratory stridor, and airway swelling can be seen on a frontal neck X-Ray indicated by a steeple sign. These cases require immediate medical intervention.

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Question 1
Which of the following is a common symptom associated with laryngotracheobronchitis (viral croup)?
A
drooling
Hint:
Drooling and a "hot potato" voice are seen with epiglottitis, not viral croup.
B
high fever
Hint:
Fever is usually absent or low grade in patients with viral croup.
C
"hot potato" voice
Hint:
See A for explanation.
D
barking cough
Question 1 Explanation: 
Viral croup is characterized by history of an upper respiratory tract symptoms followed by onset of a barking cough and stridor.
Question 2
A 2 year-old presents to the emergency department in acute respiratory distress. The parents relate a history of a recent upper respiratory illness that was followed by a sudden onset of barking cough during the night, but this morning they noted increased difficulty breathing. The child is noted to have stridor at rest, but has no evidence of cyanosis. Which of the following is the most appropriate initial intervention?
A
Intravenous antibiotics
Hint:
Laryngotracheobronchitis is caused by viruses, not bacteria, and therefore antibiotic therapy is not indicated.
B
Endotracheal intubation
Hint:
If patients fail to respond to initial treatment and progress to impending respiratory failure, endotracheal intubation is then indicated.
C
Inhaled mucolytic agent
Hint:
Inhaled mucolytic agents are not indicated in the treatment of laryngotracheobronchitis.
D
Nebulized racemic epinephrine
Question 2 Explanation: 
This patient most likely has laryngotracheobronchitis (viral croup). Treatment with nebulized racemic epinephrine and glucocorticosteroids is indicated for patients with stridor at rest.
Question 3
A 22 month-old male infant presents with one day of barking cough preceded by three days of cold symptoms. On physical examination, his axillary temperature is 100.4°F and he has no stridor at rest. Inspiratory stridor is evident when he becomes agitated during the examination. There are no signs of respiratory distress or cyanosis. Which of the following is the most appropriate treatment for this patient?
A
Nebulized albuterol
Hint:
Viral croup is an upper airway disease and there is no role for bronchodilator therapy.
B
Nebulized epinephrine
Hint:
Nebulized racemic epinephrine is only indicated in the treatment of croup in cases of moderate to severe rest stridor, respiratory distress, or hypoxia.
C
Oral amoxicillin
Hint:
Croup is almost always a viral illness and antibiotics have no role in the treatment of this condition.
D
Oral dexamethasone
Question 3 Explanation: 
Corticosteroids are beneficial in the treatment of croup. Intramuscular administration has shown no benefit over oral administration.
Question 4
An 18-month-old male presents with his parents who report symptoms of a barking cough and intermittent stridor that has worsened over the past 12 hours. They note improvement in symptoms when he was taken outdoors to the cool night air. Which of the following is the most likely organism causing this patient's symptoms
A
Rubeola virus
Hint:
See D for explanation.
B
Adenovirus
Hint:
See D for explanation.
C
Influenza virus
Hint:
See D for explanation.
D
Parainfluenza virus
Question 4 Explanation: 
Croup is most often caused by parainfluenza virus.
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References: Merck Manual · UpToDate

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