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Strabismus (ReelDx + Lecture)

VIDEO-CASE-PRESENTATION-REEL-DX

Strabismus

2 y/o with "eye drifting" x 1 month

Patient will present as → a 3-year-old girl brought to you by her mother, who is worried about her daughter's "lazy eye." She reports that her daughter's symptoms are exaggerated when she has a cold. Past medical history is negative for trauma or headaches. The patient has an asymmetric corneal light reflex, and the cover/uncover test reveals a right-sided esotropia. You refer the patient to a pediatric ophthalmologist.

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Strabismus is defined as any form of ocular misalignment. It derives from the Greek word strabismus (to squint)

  • Strabismus can be intermittent or constant
  • There are many types of strabismus, which are defined by the direction of misalignment
    • Exotropia: out-turning of eyes
    • Esotropia: in-turning of eyes (see ReelDx video in presentation tab)
    • Hypertropia: Upward deviation of eyes
    • Hypotropia: Downward deviation of eyes

Image by Adobe Stock

The cover/uncover test is used to diagnose strabismus

Treatment options can include glasses, occlusion therapy, orthoptic exercises, surgery, or a combination of these therapies.

  • Glasses are the primary treatment for a common form of strabismus—accommodative esotropia.
  • Occlusion therapy is typically used for amblyopia rather than strabismus. If occlusion therapy improves vision, occasionally, the strabismus may improve, but more importantly, better vision improves the prognosis for strabismus treatment.
  • Eye exercises (orthoptic exercises) are useful in patients with convergence insufficiency. There is no evidence that they improve typical childhood esotropia and exotropia.
Question 1
Which of the following is diagnosed by use of the cover/uncover test?
A
Adie's pupil
Hint:
Adie's pupil is a sluggish pupil reaction to light and accommodation, evaluated by papillary reaction to light.
B
Strabismus
C
Glaucoma
Hint:
Tonometry is used to measure intraocular pressure to evaluate for glaucoma.
D
Myopia
Hint:
Myopia is evaluated by using a Snellen chart.
Question 1 Explanation: 
The cover/uncover test is used to diagnose strabismus.
Question 2
In infants, the eyes should move in parallel without deviation by the age of
A
2 weeks
Hint:
See C for explanation.
B
3 months
Hint:
See C for explanation.
C
6 months
D
1 year
Hint:
See C for explanation.
Question 2 Explanation: 
Intermittent alternating convergent strabismus is frequently noted for the first 6 months of life, but referral is indicated if it persists beyond 6 months.
Question 3
A 3-year-old girl has had an inward-turning right eye for several months. The cover test confirms a constant right esotropia, and visual acuity is reduced in the right eye. The rest of her eye exam is normal. Which of the following is the most appropriate management?
A
Reassure the parents that she will outgrow it
Hint:
A constant eye turn past early infancy is not outgrown.
B
Refer to pediatric ophthalmology for glasses and amblyopia treatment
C
Recheck at her kindergarten vision screen
Hint:
Waiting another year or two can make the amblyopia permanent.
D
Start a topical antibiotic
Hint:
There is no infection.
E
Wait until age 10 to plan surgery
Hint:
Waiting until 10 misses the years when amblyopia responds best.
Question 3 Explanation: 
A constant eye turn in a toddler won't go away on its own and needs prompt referral to pediatric ophthalmology. Treatment starts with glasses for any refractive error and patching or atropine drops for the amblyopia, and surgery is used if the eyes still don't line up. The earlier it's treated, the better the chance of normal vision in both eyes.
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References: Merck Manual · UpToDate

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