10 y/o with ear pain worsening over the last 5 days (view on ReelDx)
Patient will present as → a 10-year-old boy with otalgia, worsening over the last 5-days and associated with nasal congestion. The patient is afebrile with a temperature of 98 ° F. Examination reveals edema of the external auditory canal producing an anterior and inferior displacement of the auricle with percussion tenderness posteriorly.
Acute mastoiditis is a suppurative infection of the mastoid air cells, usually a complication from preceding acute otitis media
- Clinical features include fever, otalgia, pain and erythema posterior to the ear, and forward displacement of the external ear
- Organisms: S. pneumoniae, H. influenzae, M. catarrhalis, S. aureus, S. pyogenes
IV antibiotics + drainage are the mainstay of treatment
- First-line (no recent antibiotics): Ampicillin–sulbactam IV (covers S. pneumoniae, S. pyogenes)
- If recent antibiotics or recurrent AOM: Piperacillin–tazobactam IV (adds Pseudomonas coverage)
- Add vancomycin if severe illness, sepsis, or concern for MRSA
- IV therapy for 7–10 days, then oral antibiotics to complete ~4 weeks total
Procedures
- Myringotomy ± tympanostomy tube for middle ear drainage
- Simple mastoidectomy (drains abscess, removes infected mastoid cells) if no improvement within 48 hrs or if abscess forms
Question 1 |
IV antibiotics | |
Mastoidectomy Hint: Mastoidectomy is reserved for patients with mastoiditis who fail medical therapy. | |
IM steroids Hint: IM steroids are not indicated in the treatment of mastoiditis. | |
Ventilating tube placement Hint: Ventilating tube placement is indicated in patients with auditory tube dysfunction and chronic serous otitis media. |
Question 2 |
Viral infection leading to inflammation of the mastoid air cells Hint: While viral infections can precede otitis media, mastoiditis itself is primarily bacterial in nature. | |
Bacterial infection spreading from the middle ear to the mastoid air cells | |
Allergic reaction causing inflammation of the mastoid bone Hint: This does not typically lead to mastoiditis. | |
Fungal infection affecting the external auditory canal extending to the mastoid process Hint: Fungal infections rarely cause mastoiditis. | |
Neoplastic change in the mastoid bone secondary to chronic infection Hint: Chronic infection can lead to complications, but neoplastic change is not a typical progression of mastoiditis. |
Question 3 |
Pure tone audiometry Hint: This test assesses hearing but is not useful for diagnosing mastoiditis. | |
Tympanometry Hint: Useful in diagnosing middle ear effusion but not specific for mastoiditis. | |
CT scan of the temporal bone | |
MRI of the brain Hint: While useful for intracranial complications, it is not the first-line imaging for mastoiditis. | |
Complete blood count (CBC) Hint: May show elevated white blood cells but is non-specific and does not confirm mastoiditis. |
Question 4 |
Continue the same antibiotic therapy and observe Hint: This is not appropriate if the patient is not responding to the current antibiotic regimen. | |
Switch to a different class of antibiotics Hint: While this might be considered, it is usually not sufficient in cases of non-response to initial therapy. | |
Myringotomy with or without tympanostomy tube placement Hint: This may be used in the management of otitis media but is not sufficient for mastoiditis not responding to antibiotics. | |
Mastoidectomy | |
Initiate antifungal therapy Hint: Mastoiditis is typically bacterial, not fungal, in etiology. |
Question 5 |
Oral antibiotics and observation Hint: Oral antibiotics alone are not sufficient in the treatment of mastoiditis, especially in the presence of systemic symptoms and radiographic evidence of mastoid involvement. This approach would risk further complications, including the spread of the infection. | |
High-dose intravenous antibiotics and myringotomy | |
Tympanostomy tube placement Hint: While tympanostomy tube placement may be considered in recurrent otitis media, it is not the initial treatment for acute mastoiditis. The priority in this case is to control the infection aggressively with intravenous antibiotics and possibly surgical drainage. | |
Surgical mastoidectomy Hint: Surgical mastoidectomy may be required if the infection does not respond to intravenous antibiotics and myringotomy or if there is evidence of complications such as abscess formation. However, it is not the first-line treatment and is reserved for cases where initial management fails. | |
Oral corticosteroids Hint: Oral corticosteroids are not indicated in the management of mastoiditis and could potentially worsen the infection by suppressing the immune response. The primary treatment involves controlling the infection with antibiotics and surgical intervention if necessary. |
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List |
References: Merck Manual · UpToDate

