PANCE Blueprint EENT (7%)

Scleritis

Patient will present as → a 42-year-old white female complaining of a severely painful right eye. The pain is a constant, boring pain that worsens at night and in the early morning hours and radiates to the face and periorbital region. Additionally, she reports a headache, watering of the eye, and ocular redness.

Inflammation of the sclera (the white outer coating of the eye) associated with systemic immunologic disease, such as rheumatoid arthritis

  • It causes significant eye pain (severe, deep pain)

On examination, there is ocular redness and pain on palpation of the eyeball. It can cause visual impairment

  • Labs should include screening for systemic immunologic diseases - ANCAs, ANA, CRP, ESR, Lyme, RA, ACE, RPR, etc.

Refer the patient for prompt evaluation by an ophthalmologist

  • Treatment involves topical and sometimes systemic corticosteroids

Question 1
A 69-year-old female with scleritis and has been taking 600 mg of ibuprofen three times per day. She presents for a follow-up and stated she had not had any improvement in her symptoms after 7 days. What is the next best treatment option at this time?
A
Prescribe oral prednisone 1 mg/kg/day for one month
B
Prescribe topical prednisolone acetate 1% four times per day for one week
Hint:
Topical steroids can be used as the first-line agent in addition to oral NSAID treatment.
C
Discontinue ibuprofen
Hint:
The patient has not responded to first-line treatment but requires additional treatment to manage inflammation.
D
Prescribe topical artificial tears four times per day
Hint:
Artificial tears do not manage inflammation. They may provide some relief to any ocular surface dryness present.
Question 1 Explanation: 
If there is no response with the first-line treatment of oral NSAIDs, then second-line treatment of oral steroids is indicated.
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References: Merck Manual · UpToDate

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